講座名稱：Acoustic trapping: an emerging tool in micro-array technologies

講座人：田良飛 研究員

講座時間：4月10日10:30

地點：南校區(qū)G420

講座人介紹：

田良飛研究員，博士畢業(yè)于蘇黎世聯(lián)邦理工學院；分別在德國康斯坦茨大學和英國布里斯托大學從事博士后研究工作。2019年11月加入浙江大學生物醫(yī)學工程與儀器科學學院，任“百人計劃”研究員，并擔任浙江大學附屬婦產(chǎn)科醫(yī)院及浙江大學濱江研究院兼職教授。近年來，田良飛博士在超聲操控技術(shù)領(lǐng)域取得了一系列原創(chuàng)性高水平研究成果，并探索了其在生物醫(yī)學領(lǐng)域中的應(yīng)用。先后在Nature Chemistry(2)、Nature Communications(3)等國際知名學術(shù)期刊發(fā)表論文30余篇，申請并授權(quán)發(fā)明專利8項，孵化一家生物技術(shù)企業(yè)，相關(guān)產(chǎn)品已經(jīng)進入臨床一期的測試。其研究成果先后被包括英國皇家工程協(xié)會、英國皇家化學協(xié)會和美國物理協(xié)會等專業(yè)協(xié)會會刊在內(nèi)的近40余家科技媒體報道，在業(yè)界引發(fā)了廣泛的關(guān)注。

講座內(nèi)容：

Spatial indexing is critical in experiments that require to identify and monitor hundreds to millions of individual microcompartments over a range of timescales and chemical/physical environments. This enables the high-throughput analyses of chemical/biochemical, and cellular processes, and the digital measurements of rare events in a large sample. Systematic arrangement of individual or clusters micro-compartments or cells in 2D micro-arrays provides a miniaturized platform, in which the addressability of the objects in the array can be indexed on the basis of one or more spatial variables. Typically, arrays of micro-compartments or cells with a uniform size have been prepared by microfluidics, microfabrication, printing and by application of electrical or magnetic fields. In this talk, I will present some of our recent work on how to utilize ultrasound to organize liquid droplets, lipid vesicles, and cells in 2D micro-array. I will also discuss the use of micro-array for non-equilibrium chemical sensing, protocellular differentiation, the construction of synthetic “prototissues”, exploration of localized enzyme-directed chemical communication, and design of vesicle-mediated chemical communication pathways in protocell/living cell consortia.

主辦單位：生命科學技術(shù)學院